Pregnenolone and DHEA are hormone precursors found in many organs,
including skin, which will ultimately be converted into testosterone,
estrone, and estradiol (1).* Studies indicate men and women produce
less pregnenolone and DHEA as they age, thereby decreasing the amount
available to the epidermis (outer layer of skin). This ultimately leads
to diminished skin elasticity, firmness and moisture content (2,3).*
Current work has revealed the existence of the enzyme systems required
for normal biochemical conversion and regulation of epidermal estrogens.
This is a state of the art, non-greasy, rapidly absorbed moisturizing
cream that is quick drying and provides the skin with essential re-hydrating
components.
Goldzieher reported increases in epidermis thickness along with a more
orderly cell arrangement, elastic fibrils, capillary beds and water
content when skin was exposed to topical estrogens (5).* Blau and Kanof
noticed similar effects with the estrogen precursor pregnenolone(4).*
Normal cellular metabolism, ultraviolet exposure (UV-A and UV-B), chemical
solvents and environmental toxins have been shown to produce skin damaging
free radicals. Alpha-lipoic acid (ALA), a unique fat and water-soluble
antioxidant coupled with a patented liposomal preparation containing
vitamin C, vitamin E (Oxysomes™). This liposomal preparation of
proanthocyanidins extracted from grape seeds produce a powerful line-up
against the harmful free radicals.
Alpha-lipoic acid (ALA) is a potent thiol antioxidant that has shown
the potential to protect the skin (10).* The distinctive structure of
ALA and liposomes provides enhanced transport across skin layers and
cell membranes, while their water and lipid solubility allows effective
free radical quenching both inside and outside the cell. This symbiotic
relationship is further enhanced by ALA's ability to regenerate glutathione
(6)* and various antioxidants like vitamin C and vitamin E, which have
been shown to protect against skin damage (9)*, making for the ultimate
in free radical eradication.
Furthering this "high-tech" formula is the inclusion of Borage
Oil via a patented surfactant-free micro-emulsion chosen as the base
of this cream. With patented European compounds, this formula was designed
to minimize water loss and enhance quick drying without any noticeable
oiliness, residue or "tackiness".
This moisturizing cream contains a highly purified grape seed extract
containing a 95% oligomeric proanthocyanidin complex that has undergone
several laboratory tests to validate its ability to protect the skin
from free radical damage. This combination helps restore damaged collagen
and elastin to its most resilient functional form (8). Collagen is the
primary component of the inside layer of skin (dermis) while elastin
gives the skin its strength, smoothness and elasticity.
Progesterone acts as a holding point or bond for sealing the cross
points of collagen and elastin, similar to how cement holds bricks together
in a brick wall. To remove wrinkles from the surface of the skin, we
need collagen, elastin and the binding effects of progesterone.
These statements have not been evaluated by the Food & Drug Administration
(FDA). This product is not intended to diagnose, cure, treat or prevent
any disease.